v Antibody

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Code	CSB-PA023351XA01DLU
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Target Background

Product Details

Full Product Name

Rabbit anti-Drosophila melanogaster (Fruit fly) v Polyclonal antibody

Uniprot No.

P20351

Target Names

Alternative Names

v antibody; CG5163 antibody; Tryptophan 2,3-dioxygenase antibody; TDO antibody; EC 1.13.11.11 antibody; Protein vermilion antibody; Tryptamin 2,3-dioxygenase antibody; Tryptophan oxygenase antibody; TO antibody; TRPO antibody; Tryptophan pyrrolase antibody; Tryptophanase antibody

Raised in

Rabbit

Species Reactivity

Drosophila melanogaster (Fruit fly)

Immunogen

Recombinant Drosophila melanogaster (Fruit fly) v protein

Immunogen Species

Drosophila melanogaster (Fruit fly)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB (ensure identification of antigen)

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

Lead Time

Made-to-order (14-16 weeks)

Customer Reviews and Q&A

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Target Background

Function

Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. Required during larval growth to control the level of potentially harmful free tryptophan in the hemolymph. In the adult the same reaction is the first step in the ommochrome biosynthetic pathway.

Gene References into Functions

This study evaluated the role of the vermilion gene and its mutations on heart rate. PMID: 28127944

Protein Families

Tryptophan 2,3-dioxygenase family

Database Links

KEGG: dme:Dmel_CG2155

STRING: 7227.FBpp0073242

UniGene: Dm.7748

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