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Code	CSB-PA896068XA01DLU
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Target Background

Product Details

Full Product Name

Rabbit anti-Drosophila melanogaster (Fruit fly) to Polyclonal antibody

Uniprot No.

Q9VBV3

Target Names

Alternative Names

to antibody; CG11853 antibody; Protein takeout antibody

Raised in

Rabbit

Species Reactivity

Drosophila melanogaster (Fruit fly)

Immunogen

Recombinant Drosophila melanogaster (Fruit fly) to protein

Immunogen Species

Drosophila melanogaster (Fruit fly)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB (ensure identification of antigen)

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

Lead Time

Made-to-order (14-16 weeks)

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Target Background

Function

Participates in a novel circadian output pathway that conveys temporal and food status information to feeding-relevant metabolisms and activities. Involved in male courtship behavior. In the brain-associated fat body, transcription is enhanced by the dsx and fru male-specific isoforms and repressed by the dsx female-specific isoform.

Gene References into Functions

takeout-dependent longevity is associated with altered Juvenile Hormone signaling PMID: 22940452
We show that a number of genes in the takeout gene family show male-biased expression in D. melanogaster, largely in non-reproductive tissues. PMID: 22020223
Data show that takeout levels are low in flies with reduced Pdp1epsilon and high in flies with increased amounts of Pdp1epsilon. PMID: 20133786
A loss-of-function mutation in the takeout gene reduces male courtship and synergizes with fruitless mutations, suggesting that takeout plays a redundant role with other fru-dependent factors involved in male mating behavior PMID: 12435630
takeout plays a central role as a feeding regulator and may act by modulating the circulating Juvenile Hormone level. PMID: 17401125
Drosophila Takeout gene expression varied with diurnal or circadian rhythms. These findings suggest that Apis mellifera GB19811 is not an ortholog of Takeout. PMID: 17550825

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Subcellular Location

Secreted.

Protein Families

TO family

Tissue Specificity

Expression is largely restricted to head, with limited expression detectable in cardia and crop. In entrained individuals, expression is observed in the brain cortex (region between optic lobe and central complex), photoreceptors and antennae. In asynchro

Database Links

KEGG: dme:Dmel_CG11853

STRING: 7227.FBpp0084185

UniGene: Dm.2360

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