Tbpl2 Antibody

Code CSB-PA761436XA01MO
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Product Details

Full Product Name
Rabbit anti-Mus musculus (Mouse) Tbpl2 Polyclonal antibody
Uniprot No.
Target Names
Tbpl2
Alternative Names
Tbpl2 antibody; Tbp2 antibody; Trf3 antibody; TATA box-binding protein-like protein 2 antibody; TBP-like protein 2 antibody; TATA box-binding protein-related factor 3 antibody; TBP-related factor 3 antibody
Raised in
Rabbit
Species Reactivity
Mus musculus (Mouse)
Immunogen
Recombinant Mus musculus (Mouse) Tbpl2 protein
Immunogen Species
Mus musculus (Mouse)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Transcription factor required in complex with TAF3 for the differentiation of myoblasts into myocytes. The complex replaces TFIID at specific promoters at an early stage in the differentiation process.
Gene References into Functions
  1. TRF3 is a nuclear protein that is present in all human and mouse tissues and cell lines examined PMID: 14634207
  2. Data suggest that TRF3 plays a role in early mouse development, and may also be involved in Pol I transcription. PMID: 16721357
  3. properties of a TAF3/TRF3 complex in directing transcription initiation at the Myogenin promoter PMID: 18851836
  4. TBP2 binds to promoters of misregulated genes, suggesting that TBP2 directly regulates their expression PMID: 19759265
Subcellular Location
Cytoplasm. Nucleus.
Protein Families
TBP family
Tissue Specificity
Expressed in myotubes and myofibers (at protein level). Expressed in a wide variety of tissues with highest levels in heart, lung, liver, uterus and placenta and especially the gonads. Expression is higher in the ovary than the testis, and within the ovar
Database Links
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Call us
301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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