Tctp Antibody

Code CSB-PA892845XA01DLU
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Product Details

Full Product Name
Rabbit anti-Drosophila melanogaster (Fruit fly) Tctp Polyclonal antibody
Uniprot No.
Target Names
Tctp
Alternative Names
Tctp antibody; CG4800 antibody; Translationally-controlled tumor protein homolog antibody; TCTP antibody
Raised in
Rabbit
Species Reactivity
Drosophila melanogaster (Fruit fly)
Immunogen
Recombinant Drosophila melanogaster (Fruit fly) Tctp protein
Immunogen Species
Drosophila melanogaster (Fruit fly)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Involved in calcium binding and microtubule stabilization.
Gene References into Functions
  1. TCTP may promote the progression of epithelial ovarian cancer and reduce the sensitiveness of HO8910 cells to cisplatin. PMID: 25564355
  2. TCTP has a role in regulating ATM activity to control genome stability and organ development in Drosophila melanogaster PMID: 24352200
  3. plant AtTCTP can fully rescue cell proliferation defects in Drosophila loss of function for dTCTP PMID: 20736351
  4. Our studies identify TCTP as a direct regulator of Rheb and a potential therapeutic target for tuberous sclerosis disease. PMID: 17301792
  5. Drosophila TCTP (dTCTP) displays GEF activity to Rheb and is essential for Rheb activation in organ growth PMID: 19262129

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Subcellular Location
Cytoplasm.
Protein Families
TCTP family
Database Links

KEGG: dme:Dmel_CG4800

STRING: 7227.FBpp0081820

UniGene: Dm.9988

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