TDR Antibody

Code CSB-PA880751XA01DOA
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Product Details

Full Product Name
Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) TDR Polyclonal antibody
Uniprot No.
Target Names
TDR
Alternative Names
TDR antibody; PXY antibody; At5g61480 antibody; MCI2.4 antibody; Leucine-rich repeat receptor-like protein kinase TDR antibody; EC 2.7.11.1 antibody; Protein PHLOEM INTERCALATED WITH XYLEM antibody; Tracheary element differentiation inhibitory factor receptor antibody; AtTDR antibody; TDIF receptor antibody
Raised in
Rabbit
Species Reactivity
Arabidopsis thaliana
Immunogen
Recombinant Arabidopsis thaliana TDR protein
Immunogen Species
Arabidopsis thaliana (Mouse-ear cress)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Acts with CLE41p and CLE44p peptides as a ligand-receptor pair in a signal transduction pathway involved in the regulation of procambium maintenance and polarity during vascular-tissue development. Mediates repression of tracheary element differentiation and the promotion of procambial cells formation and polar division adjacent to phloem cells in the veins.
Gene References into Functions
  1. a conserved TDIF-recognition mechanism of TDR among plant species, is reported. PMID: 27498761
  2. the crystal structure of TDIF in complex with its receptor PXY, a leucine-rich repeat receptor kinase (LRR-RK), is reported. PMID: 27055373
  3. This study delineates a TDIF-TDR-BIN2 signalling cascade that controls regulation of ARF and AUX/IAA interaction independent of auxin perception during lateral root development. [TDR] PMID: 24362628
  4. Auxin-dependent stimulation of cambium activity depends on WOX4 and its upstream regulator PXY. PMID: 21926336
  5. TDR inhibits the xylem commitment of vascular stem cells. PMID: 20729381
  6. the PXY gene encodes for a receptor-like kinase (RLK) that defines a novel role for RLKs in the meristem where it functions to maintain the cell polarity required for the orientation of cell division during vascular development PMID: 17570668

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Subcellular Location
Cell membrane; Single-pass type I membrane protein.
Protein Families
Protein kinase superfamily, Ser/Thr protein kinase family
Tissue Specificity
Widely expressed along the vascular strands. In roots and hypocotyls, confined to procambial cells.
Database Links

KEGG: ath:AT5G61480

STRING: 3702.AT5G61480.1

UniGene: At.55662

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