TEC1 Antibody

Code CSB-PA917161XA01CZD
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Product Details

Full Product Name
Rabbit anti-Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) TEC1 Polyclonal antibody
Uniprot No.
Target Names
TEC1
Alternative Names
TEC1 antibody; CAALFM_C304530CA antibody; CaO19.13329 antibody; CaO19.5908 antibody; Transcription activator TEC1 antibody
Raised in
Rabbit
Species Reactivity
Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Immunogen
Recombinant Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) TEC1 protein
Immunogen Species
Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Transcription factor which regulates genes involved in hyphal development, cell adhesion, biofilm development, and virulence. Plays a role in the formation of 'finger' morphology, a unique multicellular morphology of C.albicans induced by carbon dioxide. Regulates gene expression during intestinal colonization. Required for the expression of the secreted aspartyl proteinases SAP4, SAP5, and SAP6; but also of BCR1, PGA4, and CDC24. Moreover, a positive feedback loop between CDC24 and TEC1 contributes to an increase in active CDC42 at the tip of the germ tube which is important for hyphae formation. Regulates also the pheromone response of the white cell phenotype.
Subcellular Location
Nucleus.
Protein Families
TEC1 family
Database Links
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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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