tehB Antibody

Code CSB-PA338669XA01ENV
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Product Details

Full Product Name
Rabbit anti-Escherichia coli (strain K12) tehB Polyclonal antibody
Uniprot No.
Target Names
tehB
Alternative Names
tehB antibody; b1430 antibody; JW1426Tellurite methyltransferase antibody; EC 2.1.1.265 antibody; Chalcogen-detoxifying protein TehB antibody; Selenite methyltransferase antibody; Tellurite resistance protein TehB antibody
Raised in
Rabbit
Species Reactivity
Escherichia coli (strain K12)
Immunogen
Recombinant Escherichia coli (strain K12) tehB protein
Immunogen Species
Escherichia coli (strain K12)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
S-adenosyl-L-methionine dependent methyltransferase that catalyzes the methylation of tellurite and is responsible for tellurite resistance when present in high copy number. Can also methylate selenite and selenium dioxide. Is thus able to detoxify different chalcogens. Cannot methylate arsenic compounds.
Gene References into Functions
  1. high-resolution crystal structure of TehB with cofactor analogues S-adenosylhomocysteine and sinefungin; investigation of catalytic mechanism suggests SN2 nucleophilic attack; kinetics of chalcogen metabolism (i.e., selenium and tellurite oxyanions) PMID: 21244361
Subcellular Location
Cytoplasm. Note=Probably a peripheral membrane protein that interacts with TehA.
Protein Families
TehB family
Database Links
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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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