mtTFB2 Antibody

Code CSB-PA895611XA01DLU
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Product Details

Full Product Name
Rabbit anti-Drosophila melanogaster (Fruit fly) mtTFB2 Polyclonal antibody
Uniprot No.
Target Names
mtTFB2
Alternative Names
mtTFB2 antibody; CG3910 antibody; Dimethyladenosine transferase 2 antibody; mitochondrial antibody; EC 2.1.1.- antibody; Mitochondrial 12S rRNA dimethylase 2 antibody; Mitochondrial transcription factor B2 antibody; S-adenosylmethionine-6-N' antibody; N'-adenosyl(rRNA) dimethyltransferase 2 antibody; d-mtTFB2 antibody
Raised in
Rabbit
Species Reactivity
Drosophila melanogaster (Fruit fly)
Immunogen
Recombinant Drosophila melanogaster (Fruit fly) mtTFB2 protein
Immunogen Species
Drosophila melanogaster (Fruit fly)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Probable S-adenosyl-L-methionine-dependent methyltransferase which specifically dimethylates mitochondrial 12S rRNA at the conserved stem loop. Also required for basal transcription of mitochondrial DNA. Also regulates mitochondrial DNA copy number. Stimulates transcription independently of the methyltransferase activity.
Gene References into Functions
  1. These data demonstrate the essential role of TFB2M in mtDNA transcription, and reveal the complex cellular, biochemical, and molecular responses induced by impairment of oxidative phosphorylation during Drosophila development. PMID: 18308726
Subcellular Location
Mitochondrion.
Protein Families
Class I-like SAM-binding methyltransferase superfamily, rRNA adenine N(6)-methyltransferase family, KsgA subfamily
Database Links

KEGG: dme:Dmel_CG3910

STRING: 7227.FBpp0081651

UniGene: Dm.3939

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