TrxT Antibody

Code CSB-PA810251XA01DLU
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Product Details

Full Product Name
Rabbit anti-Drosophila melanogaster (Fruit fly) TrxT Polyclonal antibody
Uniprot No.
Target Names
TrxT
Alternative Names
TrxT antibody; CG3315 antibody; Thioredoxin-T antibody; ThioredoxinT antibody
Raised in
Rabbit
Species Reactivity
Drosophila melanogaster (Fruit fly)
Immunogen
Recombinant Drosophila melanogaster (Fruit fly) TrxT protein
Immunogen Species
Drosophila melanogaster (Fruit fly)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Probably participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. Its tissue specificity suggests a regulatory role in the germline.
Gene References into Functions
  1. ThioredoxinT, a thioredoxin with testis-specific expression, has a clear association with the Y chromosome lampbrush loops ks-1 and kl-5 in primary spermatocytes PMID: 14579129
  2. Drosophila thioredoxin can function as an anti-aging agent and as a suppressor of Parkin-associated endothelin receptor-like receptor - and poly-glutamine-induced neurotoxicity PMID: 17301052
Subcellular Location
Nucleus. Chromosome. Note=Specifically associated with the Y chromosome loops.
Protein Families
Thioredoxin family
Tissue Specificity
Testis specific. Not expressed in the embryo. Becomes progressively more strongly expressed during larval and pupal development. In testis, it is strongly expressed in young spermatocytes, and postmeiotic spermatid stages, then expression decreases at the
Database Links

KEGG: dme:Dmel_CG3315

STRING: 7227.FBpp0070722

UniGene: Dm.8001

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