TIC Antibody

Code CSB-PA839135XA01DOA
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Product Details

Full Product Name
Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) TIC Polyclonal antibody
Uniprot No.
Target Names
TIC
Alternative Names
TIC antibody; At3g22380 antibody; MCB17.12 antibody; Protein TIME FOR COFFEE antibody
Raised in
Rabbit
Species Reactivity
Arabidopsis thaliana
Immunogen
Recombinant Arabidopsis thaliana TIC protein
Immunogen Species
Arabidopsis thaliana (Mouse-ear cress)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Regulator of normal clock function. Acts in the mid to late night. Contributes to the amplitude of circadian clocks. May act on the transcriptional induction of LATE ELONGATED HYPOCOTYL (LHY). Inhibits MYC2 protein accumulation, acting as a negative factor in the JA-signaling pathway.
Gene References into Functions
  1. a loss of TIC function causes a major reprogramming of gene expression that predicts numerous developmental, metabolic, and stress-related phenotypes PMID: 23869666
  2. TIC acts as an output component of the circadian oscillator to influence jasmonic acid signaling directly. PMID: 22693280
  3. the regulation of iron homeostasis in plants is a major output of the TIC- and central oscillator-dependent signaling pathways. PMID: 19828447
  4. TIC encodes a nucleus-acting clock regulator working close to the central oscillator. PMID: 17496120
Subcellular Location
Nucleus.
Database Links

KEGG: ath:AT3G22380

STRING: 3702.AT3G22380.2

UniGene: At.21572

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