dnaaf11 Antibody

Code CSB-PA453211XA01DIL
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Product Details

Full Product Name
Rabbit anti-Danio rerio (Zebrafish) (Brachydanio rerio) dnaaf11 Polyclonal antibody
Uniprot No.
Target Names
dnaaf11
Alternative Names
lrrc6 antibody; lrrc6l antibody; Protein tilB homolog antibody; Leucine-rich repeat-containing 6-like protein antibody; Leucine-rich repeat-containing protein 6 antibody; Seahorse antibody
Raised in
Rabbit
Species Reactivity
Danio rerio (Zebrafish) (Brachydanio rerio)
Immunogen
Recombinant Danio rerio (Zebrafish) (Brachydanio rerio) dnaaf11 protein
Immunogen Species
Danio rerio (Zebrafish) (Brachydanio rerio)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Protein A/G
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Plays a crucial role in regulating cilia motility in pronephric tubules, cloaca and neural tube. Required for establishing left-right asymmetry of the body plan; controls cell fate and convergent extension (CE) movements during gastrulation, respectively, via the Wnt and the planar cell polarity (PCP) signaling pathways. Required for the proper development of renal glomeruli and tubules.
Gene References into Functions
  1. Cystic kidney gene seahorse regulates cilia-mediated processes and Wnt pathways. PMID: 18539122
  2. the function of seahorse in cilia motility is separable from its function in other cilia-related phenotypes PMID: 19395640
Subcellular Location
Cytoplasm. Dynein axonemal particle. Cell projection, cilium. Note=Localized to cytoplasmic puncta in ciliated cells. In the semicircular canal, localized to kinocilia.
Protein Families
TilB family
Tissue Specificity
Expressed in kinocilia of hair cells.
Database Links
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Call us
301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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