TIO Antibody

Datasheet

Code	CSB-PA977851XA01DOA
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Product Details
Customer Reviews and Q&A
Target Background

Product Details

Full Product Name

Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) TIO Polyclonal antibody

Uniprot No.

Q2QAV0

Target Names

TIO

Alternative Names

TIO antibody; FU antibody; At1g50240 antibody; F14I3.15 antibody; Serine/threonine-protein kinase TIO antibody; EC 2.7.11.1 antibody; Fused homolog antibody; AtFUSED antibody; Protein TWO-IN-ONE antibody; AtTIO antibody

Raised in

Rabbit

Species Reactivity

Arabidopsis thaliana

Immunogen

Recombinant Arabidopsis thaliana TIO protein

Immunogen Species

Arabidopsis thaliana (Mouse-ear cress)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB (ensure identification of antigen)

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

Lead Time

Made-to-order (14-16 weeks)

Customer Reviews and Q&A

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Target Background

Function

Plays a role in conventional modes of cytokinesis in meristems and during male gametogenesis but also acts in nonconventional modes of cytokinesis (cellularization) during female gametogenesis. Constitutes a signaling module in association with Kinesin-12 members that is required to support phragmoplast expansion and cell-plate growth in plant cells.

Gene References into Functions

TIO to dominantly inhibit male meiotic cytokinesis in a dosage-dependent manner that may involve direct binding to a component of the canonical NACK-PQR cytokinesis signaling pathway. PMID: 24146312

Subcellular Location

Cytoplasm, cytoskeleton, phragmoplast. Note=Localized to the midline of the nascent phragmoplast and remains associated with the expanding phragmoplast ring.

Protein Families

Protein kinase superfamily, Ser/Thr protein kinase family

Tissue Specificity

Ubiquitous.

Database Links

KEGG: ath:AT1G50240

STRING: 3702.AT1G50240.2

UniGene: At.43251

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