wupA Antibody

Datasheet

Code	CSB-PA024013XA01DLU
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Target Background

Product Details

Full Product Name

Rabbit anti-Drosophila melanogaster (Fruit fly) wupA Polyclonal antibody

Uniprot No.

P36188

Target Names

wupA

Alternative Names

wupA antibody; HDP antibody; TnI antibody; CG7178 antibody; Troponin I antibody; Tn I antibody; Protein heldup antibody; Protein wings apart-A antibody

Raised in

Rabbit

Species Reactivity

Drosophila melanogaster (Fruit fly)

Immunogen

Recombinant Drosophila melanogaster (Fruit fly) wupA protein

Immunogen Species

Drosophila melanogaster (Fruit fly)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB (ensure identification of antigen)

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

Lead Time

Made-to-order (14-16 weeks)

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function

Troponin I is the ATPase inhibitory subunit of troponin in the thin filament regulatory complex. Involved in the development and maintenance of muscle and nervous system. May also be involved in the cytoskeletal apparatus.

Gene References into Functions

Findings suggest that troponin-I (wupA) may be of therapeutic interest in certain types of cancer. PMID: 27437768
Regulatory mutation fliH leads to reduced levels of troponin-I and muscle hypercontraction. PMID: 25747460
In vitro motility of native thin filaments from Drosophila indirect flight muscles reveals that the held-up 2 TnI mutation affects calcium activation. PMID: 20658179

Protein Families

Troponin I family

Tissue Specificity

All isoforms are expressed in somatic muscle. Isoforms containing exon 6a1 (isoforms 1 and 2) are expressed in all muscles but highest expression is in abdominal muscle and splanchnic muscle of the gut. Isoforms containing exon 6b1 (isoforms 5, 6, 9 and 1

Database Links

KEGG: dme:Dmel_CG7178

STRING: 7227.FBpp0074298

UniGene: Dm.1717

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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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wupA Antibody

Product Details

Related Products

Customer Reviews and Q&A

Target Background