TSK Antibody

Code CSB-PA747512XA01DOA
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Product Details

Full Product Name
Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) TSK Polyclonal antibody
Uniprot No.
Target Names
TSK
Alternative Names
TSK antibody; BRU1 antibody; MGOUN3 antibody; At3g18730 antibody; MVE11.9 antibody; Protein TONSOKU antibody; Protein BRUSHY 1 antibody; Protein MGOUN 3 antibody
Raised in
Rabbit
Species Reactivity
Arabidopsis thaliana
Immunogen
Recombinant Arabidopsis thaliana TSK protein
Immunogen Species
Arabidopsis thaliana (Mouse-ear cress)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Required for cell arrangement in root and shoot apical meristems. Involved in structural and functional stabilization of chromatin and may represent a link between response to DNA damage and epigenetic gene silencing. May be involved, when interacting with TSA1, in the organization of spindle microtubules.
Gene References into Functions
  1. BRU1 has a function related to the stability of subchromosomal gene regulation in the euchromatic regions. PMID: 21705754
  2. TONSOKU(TSK)/MGOUN3/BRUSHY1 of Arabidopsis thaliana encodes a nuclear leucine-glycine-aspargine (LGN) domain protein involved in genome maintenance; TSK is required during the cell cycle. [TSK] PMID: 15746155
  3. MGO3 is required for the correct transition to flowering and this may be mediated by histone acetylation and associated changes in FLC expression. PMID: 16728410
Subcellular Location
Nucleus, nucleoplasm. Note=During anaphase, relocalizes in spots close to the ends of spindle microtubules ahead of separating chromatids.
Protein Families
Tonsoku family
Tissue Specificity
Preferentially expressed in the shoot apex than in the leaves and stems. Expressed in the shoot apex and root tips in 5-day-old seedlings. At the shoot apex it is expressed in young leaves and in broad areas between two cotyledons. Weakly or not expressed
Database Links

KEGG: ath:AT3G18730

STRING: 3702.AT3G18730.1

UniGene: At.38502

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