TRAIP Antibody

Datasheet
Code CSB-PA866296ZA01HU

Product Details

Full Product Name Rabbit anti-Homo sapiens (Human) TRAIP Polyclonal antibody
Uniprot No. Q9BWF2
Target Names TRAIP
Alternative Names E3 ubiquitin-protein ligase TRAIP (EC 2.3.2.27) (RING finger protein 206) (RING-type E3 ubiquitin transferase TRAIP) (TRAF-interacting protein), TRAIP, RNF206 TRIP
Raised in Rabbit
Species Reactivity Homo sapiens
Immunogen Recombinant Human E3 ubiquitin-protein ligase TRAIP (TRAIP) (1-469AA)
Immunogen Species Homo sapiens (Human)
Conjugate Non-conjugated
Clonality Polyclonal
Isotype IgG
Purification Method Protein A/G
Concentration It differs from different batches. Please contact us to confirm it.
Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form Liquid
Tested Applications ELISA, WB (ensure identification of antigen)
Protocols ELISA Protocol
Troubleshooting and FAQs Antibody FAQs
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time Made-to-order
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Target Data

Function E3 ubiquitin ligase acting as a negative regulator of innate immune signaling. Inhibits activation of NF-kappa-B mediated by TNF. Negatively regulates TLR3/4- and RIG-I-mediated IRF3 activation and subsequent IFNB1 production and cellular antiviral response by promoting 'Lys-48'-linked polyubiquitination of TNK1 leading to its proteasomal degradation (By similarity)
Involvement in disease Seckel syndrome 9 (SCKL9)
Subcellular Location Cytoplasm, Cytoplasm, perinuclear region, Nucleus, Nucleus, nucleolus
Database Links

HGNC: 30764

OMIM: 605958

KEGG: hsa:10293

STRING: 9606.ENSP00000328203

UniGene: Hs.517972

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