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| Code | CSB-PA697715 |
| Size | US$299 |
| Uniprot No. | Q9BWF2 |
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| Protocols | ELISA Protocol Immunohistochemistry (IHC) Protocol |
| Immunogen | Fusion protein of Human TRAIP |
| Raised in | Rabbit |
| Species Reactivity | Human |
| Tested Applications | ELISA,IHC;ELISA:1:2000-1:10000,IHC:1:30-1:150 |
| Relevance | This gene encodes a protein that contains an N-terminal RING finger motif and a putative coiled-coil domain. A similar murine protein interacts with TNFR-associated factor 1 (TRAF1), TNFR-associated factor 2 (TRAF2), and cylindromatosis. The interaction with TRAF2 inhibits TRAF2-mediated nuclear factor kappa-B, subunit 1 activation that is required for cell activation and protection against apoptosis. |
| Form | Liquid |
| Conjugate | Non-conjugated |
| Storage Buffer | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method | Antigen affinity purification |
| Isotype | IgG |
| Alias | TRAF interacting protein |
| Immunogen Species | Homo sapiens (Human) |
| Target Names | TRAIP |
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Still Have Questions? | Leave a Message or Start an on-line Chat |
| Function | E3 ubiquitin ligase acting as a negative regulator of innate immune signaling. Inhibits activation of NF-kappa-B mediated by TNF. Negatively regulates TLR3/4- and RIG-I-mediated IRF3 activation and subsequent IFNB1 production and cellular antiviral response by promoting 'Lys-48'-linked polyubiquitination of TNK1 leading to its proteasomal degradation (By similarity) |
| Involvement in disease | Seckel syndrome 9 (SCKL9) |
| Subcellular Location | Cytoplasm, Cytoplasm, perinuclear region, Nucleus, Nucleus, nucleolus |
| Database Links |
HGNC: 30764 OMIM: 605958 KEGG: hsa:10293 STRING: 9606.ENSP00000328203 UniGene: Hs.517972 |
TRAIP Antibodies for Homo sapiens (Human)
| Code | Product Name | Species Reactivity | Application |
|---|---|---|---|
| CSB-PA024157GA01HU | TRAIP Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA253236 | TRAIP Antibody | Human | ELISA,IHC |
| CSB-PA866296ZA01HU | TRAIP Antibody | Homo sapiens | ELISA, WB (ensure identification of antigen) |
| CSB-PA866296ZA01HU | TRAIP Antibody | Homo sapiens | ELISA, WB (ensure identification of antigen) |
TRAIP Proteins for Homo sapiens (Human)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP866296HU CSB-BP866296HU CSB-MP866296HU |
Recombinant Human TRAF-interacting protein(TRAIP) | Yeast Baculovirus Mammalian cell |
| CSB-EP866296HU | Recombinant Human E3 ubiquitin-protein ligase TRAIP(TRAIP) | E.coli |
| CSB-EP866296HUa0 | Recombinant Human E3 ubiquitin-protein ligase TRAIP(TRAIP) | E.coli |
2-hydroxyisobutyryl-HIST1H1C (K158) Antibody
Applications: ELISA, WB, ICC, ChIP
Species Reactivity: Human
2-hydroxyisobutyryl-HIST1H3A (K18) Antibody
Applications: ELISA, WB, ICC, IF
Species Reactivity: Human
