TRM2 Antibody

Code CSB-PA341449XA01SVG
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Product Details

Full Product Name
Rabbit anti-Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) TRM2 Polyclonal antibody
Uniprot No.
Target Names
TRM2
Alternative Names
TRM2 antibody; NUC2 antibody; NUD1 antibody; RNC1 antibody; YKR056W antibody; tRNA antibody; uracil(54)-C(5))-methyltransferase antibody; EC 2.1.1.35 antibody; Transfer RNA methyltransferase 2 antibody; tRNA(m5U54)-methyltransferase antibody
Raised in
Rabbit
Species Reactivity
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Immunogen
Recombinant Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) TRM2 protein
Immunogen Species
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Catalyzes the formation of 5-methyl-uridine at position 54 (m5U54) in all tRNA. May also have a role in tRNA stabilization or maturation.
Gene References into Functions
  1. These results propose an important role for TRM2 in DNA repair with a potential involvement of its nuclease function in homologous recombination based repair of DNA double strand break. PMID: 17205207
  2. A defective processing in absence of TRM2, with a synergistic effect of TRM2, and EXO1 in such DNA repair processing. PMID: 17534700
Protein Families
Class I-like SAM-binding methyltransferase superfamily, RNA M5U methyltransferase family
Database Links

KEGG: sce:YKR056W

STRING: 4932.YKR056W

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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