TRM5 Antibody

Datasheet
Code CSB-PA844742XA01SXV
Product Type Polyclonal Antibody
Uniprot No. Q8TFG7
Delivery Make-to-order
Immunogen Recombinant Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) TRM5 protein
Raised in Rabbit
Species Reactivity Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Tested Applications ELISA, WB (ensure identification of antigen)
Form Liquid
Conjugate Non-conjugate
Storage Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method Protein A/G
Isotype IgG
Clonality Polyclonal
Alias tRNA (guanine(37)-N1)-methyltransferase (EC 2.1.1.228) (M1G-methyltransferase) (tRNA [GM37] methyltransferase) (tRNA methyltransferase 5) trm5 SPAPB18E9.01
Immunogen Species Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Protocols ELISA Protocol
Gene Names trm5
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding.
Subcellular Location Mitochondrion matrix, Nucleus, Cytoplasm
Protein Families Class I-like SAM-binding methyltransferase superfamily, TRM5/TYW2 family
Database Links

KEGG: spo:SPAPB18E9.01

STRING: 4896.SPAPB18E9.01.1

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