TRS85 Antibody

Code CSB-PA343238XA01SVG
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Product Details

Full Product Name
Rabbit anti-Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) TRS85 Polyclonal antibody
Uniprot No.
Target Names
TRS85
Alternative Names
TRS85 antibody; GSG1 antibody; MUM1 antibody; YDR108W antibody; YD9727.04 antibody; Trafficking protein particle complex III-specific subunit 85 antibody; TRAPP III-specific subunit 85 antibody; Muddled meiosis protein 1 antibody; Sporulation protein GSG1 antibody; Transport protein particle 85 kDa subunit antibody
Raised in
Rabbit
Species Reactivity
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Immunogen
Recombinant Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) TRS85 protein
Immunogen Species
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Specific subunit of the TRAPP III complex that acts as an autophagy-specific guanine nucleotide exchange factor (GEF) for YPT1. TRS85 directs the TRAPP III complex to the phagophore assembly site (PAS) that is involved in autophagosome formation. Required for membrane expansion during autophagy and the CVT pathway. Required for sporulation. Has a role late in meiosis following DNA replication.
Gene References into Functions
  1. Trs85 directs a Ypt1 GEF, TRAPPIII, to the phagophore to promote autophagy. PMID: 20375281
  2. TRS85 (GSG1)is required for the organization of the preautophagosomal structure during selective autophagy via the Cvt pathway. PMID: 16079147
  3. Trs85 is required for nonspecific autophagy, pexophagy and the cytoplasm to vacuole targeting pathway. PMID: 16874038
Subcellular Location
Preautophagosomal structure.
Protein Families
TRS85 family
Database Links

KEGG: sce:YDR108W

STRING: 4932.YDR108W

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