trk Antibody

Code CSB-PA635517XA01DLU
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Product Details

Full Product Name
Rabbit anti-Drosophila melanogaster (Fruit fly) trk Polyclonal antibody
Uniprot No.
Target Names
trk
Alternative Names
trk antibody; CG5619 antibody; Protein trunk antibody
Raised in
Rabbit
Species Reactivity
Drosophila melanogaster (Fruit fly)
Immunogen
Recombinant Drosophila melanogaster (Fruit fly) trk protein
Immunogen Species
Drosophila melanogaster (Fruit fly)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Required for activity of the tor receptor, could be a ligand of tor. Involved in specifying terminal body pattern.
Gene References into Functions
  1. Torso interacts with both Trunk and Torso-like, which cooperate to mediate dimerization and activation of Torso at the ends of the Drosophila embryo PMID: 28087630
  2. Present and other previous studies, suggest that the function of Tsl is to mediate secretion of Trk, thus providing the mechanism for spatially restricted activation of Tor in Drosophila embryos. PMID: 26508274
  3. Data favours a scenario where Tsl functions post proteolytic processing of Trk to control localized terminal patterning. PMID: 24584029
  4. Extracellular processing of the Trunk ligand at the anterior and posterior termini of the developing embryo activates the signaling pathway that defines the two ends. PMID: 11752676
Subcellular Location
Secreted.
Protein Families
Noggin family
Database Links

KEGG: dme:Dmel_CG5619

STRING: 7227.FBpp0079667

UniGene: Dm.30825

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