tsn1 Antibody

Code CSB-PA882247XA01SXV
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Product Details

Full Product Name
Rabbit anti-Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) tsn1 Polyclonal antibody
Uniprot No.
Target Names
tsn1
Alternative Names
tsn1 antibody; mug90 antibody; SPAC30.03cTranslin-1 antibody; Meiotically up-regulated gene 90 protein antibody; Translin homolog antibody
Raised in
Rabbit
Species Reactivity
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Immunogen
Recombinant Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) tsn1 protein
Immunogen Species
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
DNA-binding protein that specifically recognizes consensus sequences at the breakpoint junctions in chromosomal translocations. Selectively binds single-stranded d(GT)n and d(GTT)n microsatellite repeats. Has much higher affinities for the homologous RNA sequences (GU)n and (GUU)n. Does not bind double-stranded DNA. Has a role in meiosis.
Gene References into Functions
  1. Translin and Trax differentially regulate telomere-associated transcript homeostasis. PMID: 27183912
  2. Bioinformatics combined with yeast two-hybrid assays and proteomic analyses of deletion variants, identified at the top of the spTranslin structure a region required for interaction with spTRAX, and for spTranslin dimerization. PMID: 20081200
  3. Translin is a non-essential, octameric protein that selectively binds ssDNA microsatellite repeats & corresponding RNA sequences but not dsDNA. Its much higher affinity for RNA repeats suggests that it's involved in RNA metabolism-related functions. [tsn] PMID: 16043634
Subcellular Location
Cytoplasm. Nucleus.
Protein Families
Translin family
Database Links
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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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