tub-1 Antibody

Code CSB-PA586697XA01CXY
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Product Details

Full Product Name
Rabbit anti-Caenorhabditis elegans tub-1 Polyclonal antibody
Uniprot No.
Target Names
tub-1
Alternative Names
tub-1 antibody; F10B5.4 antibody; Tubby protein homolog 1 antibody
Raised in
Rabbit
Species Reactivity
Caenorhabditis elegans
Immunogen
Recombinant Caenorhabditis elegans tub-1 protein
Immunogen Species
Caenorhabditis elegans
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Has a role in fat regulation independent of daf-16. Implicated in ciliar sensory function which is required for normal sensory behavior such as chemotaxis. Functions in life span control via the insulin/IGF-1 pathway. Thought to be involved in neuronal trafficking.
Gene References into Functions
  1. we define a role for tub-1 in regulation of life span and show that tub-1 regulates life span and fat storage by two independent mechanisms. PMID: 16054097
  2. Results propose that TUB-1 controls receptor or sensory molecule degradation in neurons by regulating a RAB-7-mediated endocytic pathway. PMID: 17762880
Subcellular Location
Cytoplasm. Cell projection, axon. Cell projection, dendrite. Cell projection, cilium.
Protein Families
TUB family
Tissue Specificity
Expressed in ciliated sensory neurons.
Database Links

KEGG: cel:CELE_F10B5.4

STRING: 6239.F10B5.4

UniGene: Cel.19577

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