ple Antibody

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Code	CSB-PA023470XA01DLU
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Target Background

Product Details

Full Product Name

Rabbit anti-Drosophila melanogaster (Fruit fly) ple Polyclonal antibody

Uniprot No.

P18459

Target Names

ple

Alternative Names

ple antibody; TH antibody; CG10118Tyrosine 3-monooxygenase antibody; EC 1.14.16.2 antibody; Protein Pale antibody; Tyrosine 3-hydroxylase antibody; TH antibody

Raised in

Rabbit

Species Reactivity

Drosophila melanogaster (Fruit fly)

Immunogen

Recombinant Drosophila melanogaster (Fruit fly) ple protein

Immunogen Species

Drosophila melanogaster (Fruit fly)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB (ensure identification of antigen)

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

Lead Time

Made-to-order (14-16 weeks)

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Target Background

Function

Plays an important role in the physiology of adrenergic neurons.

Gene References into Functions

The biochemically conserved regulatory mechanisms of recombinant DTH parallel those from mammals. PMID: 16187166
maternal as well as embryonic effects on the secretion and/or functionality of Tyrosine hydroxylase (pale) may play roles in the early developmental program of the organism. PMID: 17334989
activity of tyrosine hydroxylase is also increased by this interaction, in excess of the stimulation resulting from phosphorylation alone PMID: 18801743

Subcellular Location

Cytoplasm, perinuclear region.

Protein Families

Biopterin-dependent aromatic amino acid hydroxylase family

Database Links

KEGG: dme:Dmel_CG10118

STRING: 7227.FBpp0076666

UniGene: Dm.3463

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