tth-1 Antibody

Code CSB-PA237991XA01CXY
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Product Details

Full Product Name
Rabbit anti-Caenorhabditis elegans tth-1 Polyclonal antibody
Uniprot No.
Target Names
tth-1
Alternative Names
tth-1 antibody; F08F1.8 antibody; Thymosin beta antibody; Tetrathymosin beta antibody
Raised in
Rabbit
Species Reactivity
Caenorhabditis elegans
Immunogen
Recombinant Caenorhabditis elegans tth-1 protein
Immunogen Species
Caenorhabditis elegans
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Plays an important role in the organization of the cytoskeleton by regulating actin polymerization in two ways. Firstly, by binding to and sequestering actin monomers (G actin) inhibits actin polymerization. Secondly, by binding directly filamentous actin (F actin) promotes actin polymerization. Regulates the formation of cortical actin in oocytes conferring them enough rigidity to sustain the contractions during ovulation.
Gene References into Functions
  1. Data suggest that the activity of tetraThymosinbeta is of crucial importance at specific developmental stages requiring actin polymerization. PMID: 15269284
Subcellular Location
Cytoplasm, cell cortex. Cytoplasm. Cell junction. Cytoplasm, cytoskeleton.
Protein Families
Thymosin beta family
Tissue Specificity
At the comma stage, enriched in the developing nerve ring (at protein level). Ubiquitously expressed in larvae and adults with enrichment in the spermatheca, the intestinal tract and the posterior bulb of the pharynx (at protein level). Expressed in oocyt
Database Links

KEGG: cel:CELE_F08F1.8

STRING: 6239.F08F1.8.1

UniGene: Cel.4989

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