Tau-theraphotoxin-Hs1a Antibody

Datasheet

Code	CSB-PA316743ZA01HUL
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Target Background

Product Details

Full Product Name

Rabbit anti-Haplopelma schmidti (Chinese bird spider) (Ornithoctonus huwenum) Tau-theraphotoxin-Hs1a Polyclonal antibody

Uniprot No.

P0CH43

Target Names

Tau-theraphotoxin-Hs1a

Alternative Names

Tau-theraphotoxin-Hs1a (Tau-TRTX-Hs1a) (Double-knot toxin) (DkTx)

Raised in

Rabbit

Species Reactivity

Haplopelma schmidti

Immunogen

Recombinant Haplopelma schmidti Tau-theraphotoxin-Hs1a protein

Immunogen Species

Haplopelma schmidti (Chinese bird spider) (Ornithoctonus huwenum)

Conjugate

Non-conjugate

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB (ensure identification of antigen)

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

Lead Time

Made-to-order (12-14 weeks)

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function

Selectively activates the heat-activated TRPV1 channel. It binds to TRPV1 in an open state-dependent manner, trapping it there to produce irreversible currents. It binds to the outer edge of the external pore of TRPV1 in a counterclockwise configuration, using a limited protein-protein interface and inserting hydrophobic residues into the bilayer. It also partitions naturally into membranes, with the two lobes exhibiting opposing energetics for membrane partitioning (K1) and channel activation (K2). In addition, the toxin disrupts a cluster of hydrophobic residues behind the selectivity filter that are critical for channel activation.

Subcellular Location

Secreted.

Protein Families

Huwentoxin-1 family, Double-knot toxin subfamily

Tissue Specificity

Expressed by the venom gland.

Promotions

Email: [email protected]
Distributors Worldwide

Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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Tau-theraphotoxin-Hs1a Antibody

Product Details

Related Products

Customer Reviews and Q&A

Target Background