UBC4 Antibody

Code CSB-PA325375XA01SVG
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Product Details

Full Product Name
Rabbit anti-Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) UBC4 Polyclonal antibody
Uniprot No.
Target Names
UBC4
Alternative Names
UBC4 antibody; YBR082C antibody; YBR0745 antibody; Ubiquitin-conjugating enzyme E2 4 antibody; EC 2.3.2.23 antibody; E2 ubiquitin-conjugating enzyme 4 antibody; Ubiquitin carrier protein 4 antibody; Ubiquitin-protein ligase 4 antibody
Raised in
Rabbit
Species Reactivity
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Immunogen
Recombinant Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) UBC4 protein
Immunogen Species
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Catalyzes the covalent attachment of ubiquitin to other proteins. Mediates the selective degradation of short-lived and abnormal proteins. Mediates ubiquitination of PEX5.
Gene References into Functions
  1. Rad25 turnover requires the ubiquitin-conjugating enzyme Ubc4 and the ubiquitin ligase Ufd4. PMID: 25670855
  2. Data suggest that regular turnover of Cdc17 via Ubc4 and Not4 is required for proper cell proliferation. PMID: 20660159
  3. Gap1 was removed from the plasma membrane in the presence of ethanol in a Rsp5-dependent manner, and that the disappearance of Gap1 required Ubc4 and involved the lysine residues of ubiquitin. PMID: 19809202
  4. Saccharomyces cerevisiae Ub-conjugating enzyme Ubc4 binds the proteasome in the presence of translationally damaged proteins. PMID: 16118187
  5. These results point to Ubc4p as an important enzyme in the process of cell wall remodelling in myo1 cells. PMID: 17397110
  6. Ubc4 is required for Chf2-dependent G(1) cell cycle delay. PMID: 18202552

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Protein Families
Ubiquitin-conjugating enzyme family
Database Links

KEGG: sce:YBR082C

STRING: 4932.YBR082C

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