Ucp4C Antibody

Code CSB-PA134990XA01DLU
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Product Details

Full Product Name
Rabbit anti-Drosophila melanogaster (Fruit fly) Ucp4C Polyclonal antibody
Uniprot No.
Target Names
Ucp4C
Alternative Names
Ucp4C antibody; CG9064Mitochondrial uncoupling protein 4C antibody
Raised in
Rabbit
Species Reactivity
Drosophila melanogaster (Fruit fly)
Immunogen
Recombinant Drosophila melanogaster (Fruit fly) Ucp4C protein
Immunogen Species
Drosophila melanogaster (Fruit fly)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Mitochondrial protein that is likely to be responsible for thermogenic respiration. Likely to function in mitochondrial uncoupling i.e. creating mitochondrial proton leaks across the inner mitochondrial membrane and can therefore dissipate the mitochondrial proton gradient and convert the energy of substrate oxidation into heat instead of ATP. Involved in cold tolerance, it is required for development to the adult stage at low temperatures.
Gene References into Functions
  1. Uncoupled respiration of larval mitochondria required palmitate, was dependent on Ucp4C and was inhibited by guanosine diphosphate. UCP4C is required for development through the prepupal stages at low temperatures and may be an uncoupling protein. PMID: 24639557
Subcellular Location
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein Families
Mitochondrial carrier (TC 2.A.29) family
Database Links

KEGG: dme:Dmel_CG9064

STRING: 7227.FBpp0078803

UniGene: Dm.5083

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