ULS1 Antibody

Code CSB-PA600116XA01SVG
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Product Details

Full Product Name
Rabbit anti-Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) ULS1 Polyclonal antibody
Uniprot No.
Target Names
ULS1
Alternative Names
ULS1 antibody; DIS1 antibody; RIS1 antibody; TID4 antibody; YOR191W antibody; ATP-dependent helicase ULS1 antibody; EC 3.6.4.- antibody; Role in silencing protein 1 antibody; Ubiquitin ligase for SUMO conjugates protein 1 antibody
Raised in
Rabbit
Species Reactivity
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Immunogen
Recombinant Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) ULS1 protein
Immunogen Species
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
ATP-dependent helicase involved mating type switching and in silencing interference through its interaction with the silencing regulator SIR4. Cooperates with UBC4 and UBC5 to mediate ubiquitination of SUMO conjugates.
Gene References into Functions
  1. deletion of ULS1 restores stability of the rDNA region in sgs1Delta cells. PMID: 25091157
  2. End-joining inhibition at telomeres requires the translocase and polySUMO-dependent ubiquitin ligase Uls1. PMID: 23417015
  3. Deletion of ULS1 in cells lacking RAD52 caused a synthetic growth defect accompanied by prolonged S phase and aberrant cell morphology. PMID: 21764775
  4. A SUMO-binding motif of Ris1p was required for interaction with Ebp2p. PMID: 18603780
Subcellular Location
Nucleus.
Protein Families
SNF2/RAD54 helicase family
Database Links

KEGG: sce:YOR191W

STRING: 4932.YOR191W

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