umps-1 Antibody

Code CSB-PA254804XA01CXY
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Product Details

Full Product Name
Rabbit anti-Caenorhabditis elegans umps-1 Polyclonal antibody
Uniprot No.
Target Names
umps-1
Alternative Names
umps-1 antibody; rad-6 antibody; T07C4.1Uridine 5'-monophosphate synthase antibody; UMP synthase) [Includes: Orotate phosphoribosyltransferase antibody; OPRT antibody; OPRTase antibody; EC 2.4.2.10); Orotidine 5'-phosphate decarboxylase antibody; ODC antibody; ODCase antibody; EC 4.1.1.23)] antibody
Raised in
Rabbit
Species Reactivity
Caenorhabditis elegans
Immunogen
Recombinant Caenorhabditis elegans umps-1 protein
Immunogen Species
Caenorhabditis elegans
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Bifunctional enzyme which catalyzes the formation of UMP from orotate in the de novo pathway of pyrimidine biosynthesis. May also form UMP from uracil. Regulates the size of gut granules during embryonic development. Involved in resistance to DNA damaging agents including UV-C and X-ray radiation.
Gene References into Functions
  1. the conserved uridine monophosphate phosphoribosyltransferase (UMPS), which acts in pyrimidine biosynthesis, is required for NAD(+) biosynthesis in place of the missing QPRTase PMID: 28559281
Subcellular Location
Cytoplasm.
Protein Families
Purine/pyrimidine phosphoribosyltransferase family; OMP decarboxylase family
Tissue Specificity
Expressed in intestine and in neurons near the nerve ring and rectum.
Database Links

KEGG: cel:CELE_T07C4.1

STRING: 6239.T07C4.1.2

UniGene: Cel.10078

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