unc-22 Antibody

Code CSB-PA633817XA01CXY
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Product Details

Full Product Name
Rabbit anti-Caenorhabditis elegans unc-22 Polyclonal antibody
Uniprot No.
Target Names
unc-22
Alternative Names
unc-22 antibody; ZK617.1Twitchin antibody; EC 2.7.11.1 antibody; Uncoordinated protein 22 antibody
Raised in
Rabbit
Species Reactivity
Caenorhabditis elegans
Immunogen
Recombinant Caenorhabditis elegans unc-22 protein
Immunogen Species
Caenorhabditis elegans
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Regulator of muscle contraction and relaxation. Senses mechanical strain that occurs during muscle activity by unfolding in clearly resolvable steps at differing forces. Plays a role in the organization of sarcomeres in body wall muscles.
Gene References into Functions
  1. Twitchin is activated by MAK-1. Twitchin may ba also regulated by the p38 MAP kinase pathway. PMID: 25851606
Subcellular Location
Cytoplasm, myofibril, sarcomere. Cytoplasm, myofibril, sarcomere, A band.
Protein Families
Protein kinase superfamily, CAMK Ser/Thr protein kinase family
Tissue Specificity
Expressed in body wall, anal, vulval, and pharyngeal muscles (at protein level).
Database Links

STRING: 6239.ZK617.1b.2

UniGene: Cel.23028

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