unc-98 Antibody

Code CSB-PA615185XA01CXY
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Product Details

Full Product Name
Rabbit anti-Caenorhabditis elegans unc-98 Polyclonal antibody
Uniprot No.
Target Names
unc-98
Alternative Names
unc-98 antibody; F08C6.7 antibody; Zinc finger protein unc-98 antibody; Uncoordinated protein 98 antibody
Raised in
Rabbit
Species Reactivity
Caenorhabditis elegans
Immunogen
Recombinant Caenorhabditis elegans unc-98 protein
Immunogen Species
Caenorhabditis elegans
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Probable transcription factor required for muscle structure. Its dual subcellular localization suggests that it may function both as a muscle adhesion complex protein and as a transcription factor, or work together with transcription factors, to influence gene expression. Thought to act as a molecular bridge between unc-97 and myo-3 at the M-line of muscles, possibly in a signaling role. Plays a role in the formation of muscle connections, also called muscle arm extensions, between the body wall and the motor axons in the dorsal and ventral cord.
Gene References into Functions
  1. both a structural component of muscle focal adhesions and a nuclear protein that influences gene expression PMID: 12808046
Subcellular Location
Nucleus. Cytoplasm. Note=Localized in body wall muscle M-lines, dense bodies and muscle nuclei.
Tissue Specificity
Expressed in embryos from 1.5- to 2-fold stage in myofibrils. In larvae and adults, it is expressed in body wall muscle, and in addition, anal depressor muscle and vulval muscles. More specifically it is found in the thick filaments of muscle fibers.
Database Links

KEGG: cel:CELE_F08C6.7

STRING: 6239.F08C6.7

UniGene: Cel.9298

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