UPP Antibody

Code CSB-PA868119XA01DOA
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Product Details

Full Product Name
Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) UPP Polyclonal antibody
Uniprot No.
Target Names
UPP
Alternative Names
UPP antibody; PYRR antibody; At3g53900 antibody; F5K20.200 antibody; Uracil phosphoribosyltransferase antibody; chloroplastic antibody; UPRTase antibody; EC 2.4.2.9 antibody; UMP pyrophosphorylase antibody
Raised in
Rabbit
Species Reactivity
Arabidopsis thaliana
Immunogen
Recombinant Arabidopsis thaliana UPP protein
Immunogen Species
Arabidopsis thaliana (Mouse-ear cress)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Uracil phosphoribosyltransferase (UPRT) that catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate. Is probably the only functional UPRT, since the dual-domain proteins of the UKL family seem to lack this activity.
Gene References into Functions
  1. Unravelling the potential of a new uracil phosphoribosyltransferase (UPRT) from Arabidopsis thaliana in sensitizing HeLa cells towards 5-fluorouracil. PMID: 27180296
  2. the mono-domain UPP gene encodes a functional uracil phosphoribosyltransferase. Loss of UPRT activity strongly affects early Arabidopsis development. PMID: 19563437
Subcellular Location
Plastid, chloroplast.
Protein Families
UPRTase family
Database Links

KEGG: ath:AT3G53900

STRING: 3702.AT3G53900.2

UniGene: At.20036

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