ureG Antibody

Datasheet

Code	CSB-PA600965XA01HUV
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Product Details

Full Product Name

Rabbit anti-Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori) ureG Polyclonal antibody

Uniprot No.

Q09066

Target Names

ureG

Alternative Names

ureG antibody; HP_0068 antibody; Urease accessory protein UreG antibody

Raised in

Rabbit

Species Reactivity

Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori)

Immunogen

Recombinant Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori) ureG protein

Immunogen Species

Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB (ensure identification of antigen)

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

Lead Time

Made-to-order (14-16 weeks)

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function

Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.

Gene References into Functions

The crystal structure of the UreD-UreF-UreG complex from the human pathogen Helicobacter pylori (HpUreDFG) revealed the presence of tunnels that cross the entire length of both UreF and UreD, potentially able to deliver Ni(II) ions from UreG to apo-urease. PMID: 28379694
The rUreG protein was successfully cloned and expressed and showed good reactivity with H. pylori culture-positive patients' sera and no reactivity with most control sera. PMID: 25406411
Results suggest that the C-terminal residues and helix alpha2 of UreF are essential for the recruitment of UreG for the formation of the pre-activation complex. PMID: 22013070

Subcellular Location

Cytoplasm.

Protein Families

SIMIBI class G3E GTPase family, UreG subfamily

Database Links

KEGG: heo:C694_00325

STRING: 85962.HP0068

Promotions

Email: [email protected]
Distributors Worldwide

Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

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Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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ureG Antibody

Product Details

Related Products

Customer Reviews and Q&A

Target Background