uri Antibody

Code CSB-PA565242XA01DLU
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Product Details

Full Product Name
Rabbit anti-Drosophila melanogaster (Fruit fly) uri Polyclonal antibody
Uniprot No.
Target Names
uri
Alternative Names
uri antibody; ori antibody; CG11416Unconventional prefoldin RPB5 interactor-like protein antibody
Raised in
Rabbit
Species Reactivity
Drosophila melanogaster (Fruit fly)
Immunogen
Recombinant Drosophila melanogaster (Fruit fly) uri protein
Immunogen Species
Drosophila melanogaster (Fruit fly)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Inhibits the activity of serine/threonine-protein phosphatases flw/PP1beta9C and Pp1-87B. Required for germ line cell viability and differentiation, normal transcriptional activity and maintenance of DNA integrity.
Gene References into Functions
  1. Uri is the first PP1alpha specific binding protein to be described in Drosophila. Uri protein plays a role in transcriptional regulation. Activity of uri is required to maintain DNA integrity and cell survival in normal development. PMID: 18412953
Subcellular Location
Cytoplasm. Chromosome. Nucleus.
Protein Families
RNA polymerase II subunit 5-mediating protein family
Database Links

KEGG: dme:Dmel_CG11416

STRING: 7227.FBpp0072215

UniGene: Dm.774

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