wcd Antibody

Code CSB-PA895105XA01DLU
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Product Details

Full Product Name Rabbit anti-Drosophila melanogaster (Fruit fly) wcd Polyclonal antibody
Uniprot No. Q9V7P1
Target Names wcd
Alternative Names wcd antibody; l(2)k07824 antibody; CG7989 antibody; U3 small nucleolar RNA-associated protein 18 homolog antibody; Protein wicked antibody; WD repeat protein l(2)k07824 antibody
Raised in Rabbit
Species Reactivity Drosophila melanogaster (Fruit fly)
Immunogen Recombinant Drosophila melanogaster (Fruit fly) wcd protein
Immunogen Species Drosophila melanogaster (Fruit fly)
Conjugate Non-conjugated
Clonality Polyclonal
Isotype IgG
Purification Method Protein A/G
Concentration It differs from different batches. Please contact us to confirm it.
Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form Liquid
Tested Applications ELISA, WB (ensure identification of antigen)
Protocols ELISA Protocol
Troubleshooting and FAQs Antibody FAQs
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables ① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee ① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time Made-to-order (14-16 weeks)

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Target Background

(From Uniprot)
Component of a nucleolar small nuclear ribonucleoprotein particle (snoRNP) thought to participate in the processing and modification of pre-ribosomal RNA. Regulation of cell size by ribosome synthesis is an important parameter for stem cell maintenance and function.
Gene References into Functions
  1. Results describe mutations in a Drosophila melanogaster gene, wicked (wcd, CG7989), which induce premature differentiation of germline stem cells (GSCs), and show that Wcd is a member of the U3 snoRNP complex required for pre-ribosomal RNA maturation. PMID: 19430468
Subcellular Location Nucleus, nucleolus. Note=Asymmetric segregation of expression upon mitosis both in germline stem cells (GSCs) and dividing larval neural stem cells (NSCs) (at protein level).
Protein Families WD repeat UTP18 family
Database Links

KEGG: dme:Dmel_CG7989

STRING: 7227.FBpp0086314

UniGene: Dm.11287

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