VDAC4 Antibody

Code CSB-PA884275XA01DOA
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Product Details

Full Product Name
Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) VDAC4 Polyclonal antibody
Uniprot No.
Target Names
VDAC4
Alternative Names
VDAC4 antibody; At5g57490 antibody; MUA2.6Mitochondrial outer membrane protein porin 4 antibody; Voltage-dependent anion-selective channel protein 4 antibody; AtVDAC4 antibody; VDAC-4 antibody
Raised in
Rabbit
Species Reactivity
Arabidopsis thaliana
Immunogen
Recombinant Arabidopsis thaliana VDAC4 protein
Immunogen Species
Arabidopsis thaliana (Mouse-ear cress)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Forms a channel through the mitochondrial outer membrane that allows diffusion of small hydrophilic molecules. The channel adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV. The open state has a weak anion selectivity whereas the closed state is cation-selective. Involved in plant growth and development at the vegetative and reproductive stages. Is important for leaf and pollen development and mitochondrial membrane potential steady state. May be involved in disease resistance.
Gene References into Functions
  1. AtVDAC4 has a main function in mitochondria PMID: 22294207
  2. VDAC2 and VDAC4 are important for leaf development, the mitochondrial membrane potential, and pollen development. PMID: 21705391
Subcellular Location
Cell membrane. Mitochondrion outer membrane. Note=Also localized in other unidentified cellular compartments.
Protein Families
Eukaryotic mitochondrial porin (TC 1.B.8.1) family
Tissue Specificity
Widely expressed.
Database Links

KEGG: ath:AT5G57490

STRING: 3702.AT5G57490.1

UniGene: At.23756

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