vg Antibody

1. High hydrostatic pressure-induced wing mutagenesis in Drosophila melanogaster resulted in 285 differentially expressed genes and two point mutations in the vestigial gene. PMID: 26446369
2. Data show that genes araucan and caupolican as novel muscle identity genes that confer lateral transverse muscle identity, and the acquisition of this fate requires that Araucan/Caupolican repress other muscle identity genes such as slouch and vestigial. PMID: 21811416
3. Studies indicate that negative regulation of the Vestigial gradient by Wingless signaling makes vestigial expression precise and robust. PMID: 20932848
4. Vg is a key factor to induce specific changes in ventral longitudinal muscles 1-4 identity and is required for these cells to be competent to form stable intermuscular attachments with each other. PMID: 20685961
5. We show that the ectopic expression of vestigial only induces ectopic outgrowths with wing cuticular differentiation and wing blade gene expression patterns in specific developmental and genetic contexts. PMID: 12441303
6. A negative association between the vg expressiveness and the degree of chromosome polyteny was revealed and proved to be stronger in females than in males. PMID: 12575446
7. vg appears to be a key regulatory gene of IFM development PMID: 12921740
8. a critical player for both cell proliferation and cell survival in the presumptive wing margin area PMID: 14526388
9. Sumoylation by SUMO stimulates Vg function during wing morphogenesis. PMID: 16026969
10. Differences in vestigial expression between neighboring cells of the wing blade autonomously and nonautonomously affect cell proliferation along the proximo-distal axis. PMID: 16950871
11. Control of Drosophila wing growth by the vestigial quadrant enhancer. PMID: 17634191
12. Data show that both Vestigial and Scalloped are required for muscle differentiation, as loss of either leads to a loss of a subset of either cardiac or somatic muscle cells in developing embryos, and also that Sd, Vg, and Dmef2 can interact directly. PMID: 18987343
13. Data show that vestigial is controlled by the Notch anti-myogenic signaling pathway in myoblasts and is regulated by a novel 822 bp enhancer during indirect flight muscle differentiation. PMID: 19500564

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KEGG: dme:Dmel_CG3830

STRING: 7227.FBpp0086898