WHY1 Antibody

Code CSB-PA583808XA01DOA
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Product Details

Full Product Name
Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) WHY1 Polyclonal antibody
Uniprot No.
Target Names
WHY1
Alternative Names
WHY1 antibody; PTAC1 antibody; At1g14410 antibody; F14L17.18 antibody; Single-stranded DNA-binding protein WHY1 antibody; chloroplastic antibody; Protein PLASTID TRANSCRIPTIONALLY ACTIVE 1 antibody; Protein WHIRLY 1 antibody; AtWHY1 antibody
Raised in
Rabbit
Species Reactivity
Arabidopsis thaliana
Immunogen
Recombinant Arabidopsis thaliana WHY1 protein
Immunogen Species
Arabidopsis thaliana (Mouse-ear cress)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Single-stranded DNA-binding protein that functions in both chloroplasts and nucleus. In chloroplasts, maintains plastid genome stability by preventing break-induced and short homology-dependent illegitimate recombinations. In nucleus, modulates telomere length homeostasis by inhibiting the action of the telomerase at the extreme termini of chromosomes. Is recruited to a distal element upstream of the kinesin KP1 to mediate the transcriptional repression of KP1. Is required for full salicylic acid-dependent plant disease resistance responses. Can bind double-stranded DNA in vivo.
Gene References into Functions
  1. The redox state of the photosynthetic electron transport chain triggers the movement of WHIRLY1 from the chloroplasts to the nucleus. PMID: 24591713
  2. Whirly1 is translocated from the plastid to the nucleus where it affects expression of target genes such as PR1. [Whirly1] [WHY1] PMID: 22154598
  3. AtWHY1 is a new family of telomere end-binding proteins that plays a role in regulating telomere-length homeostasis in Arabidopsis. [Whirly 1][AtWHY1] PMID: 17217467
Subcellular Location
Plastid, chloroplast. Nucleus. Note=Can localize to both chloroplast and nucleus (PubMed:15967440).
Protein Families
Whirly family
Database Links

KEGG: ath:AT1G14410

STRING: 3702.AT1G14410.1

UniGene: At.12043

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