Wnt5 Antibody

1. The pool of ADP-ribosylated Axin, which is degraded under basal conditions, increases immediately following Wnt stimulation in both Drosophila and human cells. PMID: 27138857
2. Wnt5 promotes dendrite termination on the periphery of sternites through the Ryk receptor family kinase Derailed (Drl) and the Rho GTPase guanine nucleotide exchange factor Trio in C4da neurons PMID: 26302791
3. Wnt5 is required for projection neurons dendrites migration and targeting in the developing antennal lobe. PMID: 25378162
4. WNT5 interacts with doughnut and derailed to mediate muscle attachment site selection PMID: 22403643
5. Wnt5 is broadly expressed in the developing brain and regulates axonal development of mushroom body neurons. PMID: 21451033
6. Derailed keeps axons out of the posterior commissure by acting as a receptor for Wnt5 PMID: 12660735
7. Wnt5 protein is predominantly present on posterior commissural axons and at a low level on the anterior commissure and longitudinal projections PMID: 15282154
8. WNT5 is required intrinsically within mushroom bodies neurons for proper axonal growth and probably interacts with the extrinsic DRL receptor in order to stop axonal growth. PMID: 17652353
9. The wnt5 as an anterograde signal that is expressed by olfactory axons and demonstrate a previously unappreciated, yet powerful, role for glia in patterning the Drosophila olfactory map. PMID: 17934456
10. Wnt5 regulates the growth of the Drosophila neuromuscular junction (NMJ) by signaling through the Derailed receptor. PMID: 17963254
11. Src family kinases play novel roles in WNT5/Derailed-mediated signaling PMID: 18539923
12. Derailed protein (Drl) and derailed protein-2 (Drl-2) play opposing roles in Wnt5 signaling during olfactory system development, depending upon the type of cells in which they are expressed. PMID: 19369566

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KEGG: dme:Dmel_CG6407

STRING: 7227.FBpp0074394

UniGene: Dm.5375