wntD Antibody

Code CSB-PA893749XA01DLU
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Product Details

Full Product Name
Rabbit anti-Drosophila melanogaster (Fruit fly) wntD Polyclonal antibody
Uniprot No.
Target Names
wntD
Alternative Names
wntD antibody; Wnt8 antibody; CG8458Wnt inhibitor of Dorsal protein antibody; Protein Wnt-8 antibody; dWnt-8 antibody
Raised in
Rabbit
Species Reactivity
Drosophila melanogaster (Fruit fly)
Immunogen
Recombinant Drosophila melanogaster (Fruit fly) wntD protein
Immunogen Species
Drosophila melanogaster (Fruit fly)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Binds as a ligand to a family of frizzled seven-transmembrane receptors and acts through a cascade of genes on the nucleus.
Gene References into Functions
  1. Study established that WntD and Die are 2 cytokines that regulate independently the expression of edin during infection by an intracellular bacteria and a virus, respectively. PMID: 27314646
  2. WntD accumulates until the Toll gradient narrows to its desired spread PMID: 26906736
  3. Crystal structure of the wntD indicate conformational plasticity in the N-terminal domain. PMID: 23791946
Subcellular Location
Secreted, extracellular space, extracellular matrix.
Protein Families
Wnt family
Database Links

KEGG: dme:Dmel_CG8458

STRING: 7227.FBpp0082243

UniGene: Dm.5874

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