MGS1 Antibody

Code CSB-PA340215XA01SVG
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Product Details

Full Product Name
Rabbit anti-Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) MGS1 Polyclonal antibody
Uniprot No.
Target Names
MGS1
Alternative Names
MGS1 antibody; YNL218W antibody; N1302 antibody; DNA-dependent ATPase MGS1 antibody; Maintenance of genome stability protein 1 antibody
Raised in
Rabbit
Species Reactivity
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Immunogen
Recombinant Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) MGS1 protein
Immunogen Species
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Involved in the maintenance of proper DNA topology and chromosome integrity via annealing of single-stranded DNA breaks. Modulates DNA polymerase delta during replication or replication-associated repair. May function as a modulator for SGS1 when DNA is damaged.
Gene References into Functions
  1. Mgs1 is a negative regulator of DNA polymerase zeta in ultraviolet mutagenesis. PMID: 24819597
  2. By means of preferential physical interactions with the ubiquitylated forms of the replicative sliding clamp, proliferating cell nuclear antigen, the UBZ domain facilitates recruitment of Mgs1 to sites of replication stress. PMID: 21911365
  3. Mgs1 is involved in Okazaki fragment processing via modulation of Fen1 activity. PMID: 16251400
Subcellular Location
Nucleus.
Protein Families
AAA ATPase family, RarA/MGS1/WRNIP1 subfamily
Database Links

KEGG: sce:YNL218W

STRING: 4932.YNL218W

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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