wrm-1 Antibody

1. Our data support a model in which WRM-1, which can undergo homotypic interaction, binds LIT-1 and thereby generates a kinase complex in which LIT-1 molecules are situated in a conformation enabling autophosphorylation. PMID: 25548171
2. model in which Wnt signaling and CDK-1 modify WRM-1 in a temporal and spatial manner to unmask an intrinsic polarity cue required for proper orientation of the endomesoderm cell division axis PMID: 23431196
3. Study shows that during telophase of an asymmetric division in C. elegans, extrinsic Wnt signaling modulates spindle structures through APR-1/APC, which in turn promotes asymmetrical nuclear localization of WRM-1/beta-catenin and POP-1/TCF. PMID: 21925317
4. Animals with reduced function of the beta-catenins SYS-1 and WRM-1 have as few as three seam cells. The 'Wnt/beta-catenin asymmetry' pathway is required for the proper stem cell-like asymmetric division of seam cells. PMID: 20849842
5. WRM-1 downregulates POP-1 by promoting its phosphorylation by the MAP kinase LIT-1 and subsequent nuclear export via a 14-3-3 protein, PAR-5. PMID: 15066285
6. Wnt signals release cortical WRM-1 from the posterior cortex to generate cortical asymmetry that may control WRM-1 asymmetric nuclear localization by regulating cell polarity PMID: 16077003
7. asymmetry in C. elegan embryos is driven by Wnt signaling PMID: 16077004
8. WRM-1 causes all SGP daughters to adopt the proximal fate. PMID: 16890160

Show More

Hide All

KEGG: cel:CELE_B0336.1

STRING: 6239.B0336.1

UniGene: Cel.16964