gpt Antibody

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Code	CSB-PA359321XA01ENV
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Product Details

Full Product Name

Rabbit anti-Escherichia coli (strain K12) gpt Polyclonal antibody

Uniprot No.

P0A9M5

Target Names

gpt

Alternative Names

gpt antibody; gpp antibody; gxu antibody; b0238 antibody; JW0228 antibody; Xanthine phosphoribosyltransferase antibody; EC 2.4.2.22 antibody; Xanthine-guanine phosphoribosyltransferase antibody; XGPRT antibody

Raised in

Rabbit

Species Reactivity

Escherichia coli (strain K12)

Immunogen

Recombinant Escherichia coli (strain K12) gpt protein

Immunogen Species

Escherichia coli (strain K12)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB (ensure identification of antigen)

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

Lead Time

Made-to-order (14-16 weeks)

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function

Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines guanine and xanthine to form the corresponding ribonucleotides GMP (guanosine 5'-monophosphate) and XMP (xanthosine 5'-monophosphate), with the release of PPi. To a lesser extent, also acts on hypoxanthine. Does not ribophosphorylate adenine.

Gene References into Functions

Report chemical structure-related mechanisms underlying in vivo genotoxicity induced by nitrofurantoin and its constituent moieties in gpt delta rats. PMID: 25772432
Data suggest that arsenite induces guanine phosphoribosyltransferase gpt G:C to T:A transversions through oxidative-stress-induced 8-OHdG formation. PMID: 24333349

Subcellular Location

Cell inner membrane; Peripheral membrane protein.

Protein Families

Purine/pyrimidine phosphoribosyltransferase family, XGPT subfamily

Database Links

KEGG: ecj:JW0228

STRING: 316385.ECDH10B_0220

Promotions

Email: [email protected]
Distributors Worldwide

Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

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Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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gpt Antibody

Product Details

Related Products

Customer Reviews and Q&A

Target Background