UVH1 Antibody

Code CSB-PA881748XA01DOA
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Product Details

Full Product Name
Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) UVH1 Polyclonal antibody
Uniprot No.
Target Names
UVH1
Alternative Names
UVH1 antibody; RAD1 antibody; At5g41150 antibody; MEE6.22 antibody; DNA repair endonuclease UVH1 antibody; EC 3.1.-.- antibody; DNA excision repair protein XP-F homolog antibody; Ultraviolet hypersensitive 1 antibody; AtRAD1 antibody
Raised in
Rabbit
Species Reactivity
Arabidopsis thaliana
Immunogen
Recombinant Arabidopsis thaliana UVH1 protein
Immunogen Species
Arabidopsis thaliana (Mouse-ear cress)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Seems to be involved in nucleotide excision repair (NER) of damaged DNA (dark repair mechanism). Involved in repair of UV light, and probably oxidative damage. The UVH1/RAD1-ERCC1/RAD10 complex may act as an endonuclease making DNA incision 5' to the lesion site. In vitro, is implicated in double strand breaks (DSBs) repair and is required for homologous recombination in the presence of non-homologous overhangs. May mediate the induction of a DNA-damage sensitive cell-cycle checkpoint during the G2 phase.
Subcellular Location
Nucleus.
Protein Families
XPF family
Tissue Specificity
Isoform 1 and isoform 2 are widely expressed, predominantly in flowers, meristems and stems. Isoform 3 is detected at low levels.
Database Links

KEGG: ath:AT5G41150

STRING: 3702.AT5G41150.1

UniGene: At.6598

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