cse1l Antibody

Code CSB-PA766464XA01DIL
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Product Details

Full Product Name
Rabbit anti-Danio rerio (Zebrafish) (Brachydanio rerio) cse1l Polyclonal antibody
Uniprot No.
Target Names
cse1l
Alternative Names
cse1l antibody; xpo2 antibody; Exportin-2 antibody; Exp2 antibody; Chromosome segregation 1-like protein antibody; Importin-alpha re-exporter antibody
Raised in
Rabbit
Species Reactivity
Danio rerio (Zebrafish) (Brachydanio rerio)
Immunogen
Recombinant Danio rerio (Zebrafish) (Brachydanio rerio) cse1l protein
Immunogen Species
Danio rerio (Zebrafish) (Brachydanio rerio)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Export receptor for importin alpha. Mediates importin-alpha re-export from the nucleus to the cytoplasm after import substrates have been released into the nucleoplasm. Negatively regulates fluid secretion and plays a role in fluid homeostasis by downregulating cftr activity.
Gene References into Functions
  1. Cse1l is a negative regulator of cystic fibrosis transmembrane conductance regulator-dependent fluid secretion. PMID: 20933420
Subcellular Location
Cytoplasm. Nucleus. Apical cell membrane; Peripheral membrane protein. Basal cell membrane; Peripheral membrane protein. Lateral cell membrane; Peripheral membrane protein.
Protein Families
XPO2/CSE1 family
Tissue Specificity
Detected in larval gut, liver, exocrine pancreas and part of the brain and retina at 96 hpf.
Database Links
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Call us
301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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