zbtb16a Antibody

Code CSB-PA801902XA01DIL
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Product Details

Full Product Name
Rabbit anti-Danio rerio (Zebrafish) (Brachydanio rerio) zbtb16a Polyclonal antibody
Uniprot No.
Target Names
zbtb16a
Alternative Names
zbtb16a antibody; plzfa antibody; zbtb16 antibody; zgc:55675 antibody; Zinc finger and BTB domain-containing protein 16-A antibody; Promyelocytic leukemia zinc finger protein-A antibody; Zinc finger protein PLZF-A antibody
Raised in
Rabbit
Species Reactivity
Danio rerio (Zebrafish) (Brachydanio rerio)
Immunogen
Recombinant Danio rerio (Zebrafish) (Brachydanio rerio) zbtb16a protein
Immunogen Species
Danio rerio (Zebrafish) (Brachydanio rerio)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Protein A/G
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Probable transcription factor. Probable substrate-recognition component of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Inhibits neurogenesis.
Gene References into Functions
  1. the results provide strong evidence that zbtb16a loss of function is associated with a partially penetrant severe cardiac development defect. PMID: 29974860
  2. Although zbtb16a and zbtb16b are not modulated by IFN produced during viral infection, their over-expression increases the level of the early type I IFN response, at a critical phase in the race between the virus and the host response. PMID: 26719025
Subcellular Location
Nucleus. Cytoplasm.
Protein Families
Krueppel C2H2-type zinc-finger protein family
Tissue Specificity
During early stages of primary neurogenesis, expressed in the neural epithelium, with highest levels in the forebrain and midbrain. Also expressed in a posterior-to-anterior gradient in the caudal neural plate at the 3-6 somite stage.
Database Links
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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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