zen Antibody

Code CSB-PA362590XA01DLU
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Product Details

Full Product Name
Rabbit anti-Drosophila melanogaster (Fruit fly) zen Polyclonal antibody
Uniprot No.
Target Names
zen
Alternative Names
zen antibody; z1 antibody; zen1 antibody; CG1046 antibody; Protein zerknuellt 1 antibody; ZEN-1 antibody
Raised in
Rabbit
Species Reactivity
Drosophila melanogaster (Fruit fly)
Immunogen
Recombinant Drosophila melanogaster (Fruit fly) zen protein
Immunogen Species
Drosophila melanogaster (Fruit fly)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Required for the differentiation of the dorsal-ventral pattern, and does not appear to be involved in the process of segmentation.
Gene References into Functions
  1. early expression of zen and its targets egr and cv-2 comprise a genetic network that canalizes embryonic dorsal-ventral patterning PMID: 25482877
  2. Eiger and Cv-2 genes are activated by Zen in Drosophila embryo. PMID: 24184102
  3. Mutational analysis shows that the number of Smad- and Zen-binding sites is essential for the C15 transcriptional response, and the spatial limits of C15 expression are established through a repression mechanism in the dorsolateral cells of the embryo. PMID: 17092951
Subcellular Location
Nucleus.
Database Links

KEGG: dme:Dmel_CG1046

STRING: 7227.FBpp0081170

UniGene: Dm.27227

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