ZER1 Antibody

Code CSB-PA800229XA01HU
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) ZER1 Polyclonal antibody
Uniprot No.
Target Names
ZER1
Alternative Names
C9orf60 antibody; chromosome 9 open reading frame 60 antibody; homolog of Zyg 11 antibody; Hzyg antibody; Protein zer-1 homolog antibody; zer 1 homolog (C elegans) antibody; ZER1 antibody; ZER1_HUMAN antibody; ZYG antibody; zyg 11 homolog B (C elegans) like antibody; Zyg 11 homolog B like protein antibody; ZYG homolog antibody; Zyg-11 homolog B-like protein antibody
Raised in
Rabbit
Species Reactivity
Homo sapiens (Human)
Immunogen
Recombinant Homo sapiens (Human) ZER1 protein
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Serves as substrate adapter subunit in the E3 ubiquitin ligase complex ZYG11B-CUL2-Elongin BC. Acts redudantly with ZYG11B to target substrates bearing N-terminal glycine degrons for proteasomal degradation. Involved in the clearance of proteolytic fragments generated by caspase cleavage during apoptosis since N-terminal glycine degrons are strongly enriched at caspase cleavage sites. Also important in the quality control of protein N-myristoylation in which N-terminal glycine degrons are conditionally exposed after a failure of N-myristoylation.
Protein Families
Zyg-11 family
Tissue Specificity
Expressed in testis, spermatocytes and spermatids (at protein level). Expressed in spermatocytes, spermatids, prostate, skeletal muscle, ovary, small intestine, heart, brain and pancreas.
Database Links

HGNC: 30960

OMIM: 617764

KEGG: hsa:10444

STRING: 9606.ENSP00000291900

UniGene: Hs.147950

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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