znf703 Antibody

Code CSB-PA026966XA01DIL
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Product Details

Full Product Name
Rabbit anti-Danio rerio (Zebrafish) (Brachydanio rerio) znf703 Polyclonal antibody
Uniprot No.
Target Names
znf703
Alternative Names
znf703 antibody; nlz antibody; nlz1 antibody; noz1 antibody; si:dkey-158j20.1 antibody; Zinc finger protein 703 antibody; NocA-like zinc finger protein 1 antibody; NocA-related zinc finger protein 1 antibody
Raised in
Rabbit
Species Reactivity
Danio rerio (Zebrafish) (Brachydanio rerio)
Immunogen
Recombinant Danio rerio (Zebrafish) (Brachydanio rerio) znf703 protein
Immunogen Species
Danio rerio (Zebrafish) (Brachydanio rerio)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Transcriptional corepressor which does not bind directly to DNA and may regulate transcription through recruitment of histone deacetylases to gene promoters. Required for segmental gene expression during hindbrain development. May regulate cell adhesion, migration and proliferation.
Gene References into Functions
  1. Nlz1 is required for cilia formation in zebrafish embryogenesis. PMID: 26327644
  2. nlz1 is expressed in the presumptive hindbrain and midbrain/hindbrain boundary. nlz2 is uniquely expressed more anteriorly, in the presumptive midbrain and diencephalon. PMID: 15042707
  3. Nlz1/Znf703 acts as a repressor of transcription PMID: 19014486
  4. identify misregulation of pax2 in the developing eye of morphant fish, suggesting that Nlz1 and Nlz2 act upstream of the Pax2 pathway in directing proper closure of the optic fissure PMID: 19171890
Subcellular Location
Nucleus. Cytoplasm.
Protein Families
Elbow/Noc family
Database Links
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Call us
301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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