alp1 Antibody

Code CSB-PA329798ZA01NGS
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Product Details

Full Product Name
Rabbit anti-Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) (Aspergillus fumigatus) alp1 Polyclonal antibody
Uniprot No.
Target Names
alp1
Alternative Names
alp1 antibody; alk1 antibody; alp antibody; AFUA_4G11800 antibody; Alkaline protease 1 antibody; ALP antibody; EC 3.4.21.63 antibody; Aspergillopeptidase B antibody; Aspergillus proteinase B antibody; Elastase antibody; Elastinolytic serine proteinase antibody; Oryzin antibody; allergen Asp f 13 antibody
Raised in
Rabbit
Species Reactivity
Neosartorya fumigata
Immunogen
Recombinant Neosartorya fumigata alp1 protein
Immunogen Species
Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) (Aspergillus fumigatus)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (12-14 weeks)

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Target Background

Function
Secreted alkaline protease that allows assimilation of proteinaceous substrates. Acts as a significant virulence factor in invasive aspergillosis. Involved in immune evasion from the human and mice complement systems during infection. Efficiently cleaves important components of the complement cascade such as such as C3, C4, C5, and C1q, as well as IgG, which leads to down-regulation of complement activation at the hyphal surface.
Subcellular Location
Secreted.
Protein Families
Peptidase S8 family
Database Links
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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