alp1 Antibody

Datasheet
Code CSB-PA329798ZA01NGS
Uniprot No. P28296
Delivery Make-to-order
Immunogen Recombinant Neosartorya fumigata Alkaline protease 1 (alp1) (102-403AA)
Raised in Rabbit
Species Reactivity Neosartorya fumigata
Tested Applications ELISA, WB (ensure identification of antigen)
Form Liquid
Conjugate Non-conjugate
Storage Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method Protein A/G
Isotype IgG
Clonality Polyclonal
Alias Alkaline protease 1 (ALP) (EC 3.4.21.63) (Aspergillopeptidase B) (Aspergillus proteinase B) (Elastase) (Elastinolytic serine proteinase) (Oryzin) (allergen Asp f 13), alp1, alk1 alp
Immunogen Species Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) (Aspergillus fumigatus)
Protocols ELISA Protocol
Gene Names alp1
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Secreted alkaline protease that allows assimilation of proteinaceous substrates. Acts as a significant virulence factor in invasive aspergillosis. Involved in immune evasion from the human and mice complement systems during infection. Efficiently cleaves important components of the complement cascade such as such as C3, C4, C5, and C1q, as well as IgG, which leads to down-regulation of complement activation at the hyphal surface.
Subcellular Location Secreted
Protein Families Peptidase S8 family
Database Links

KEGG: afm:AFUA_4G11800

STRING: 5085.CADAFUBP00006700

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alp1 Proteins for Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) (Aspergillus fumigatus)

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